![]() These results suggest that a normal PEF obtained by a peak flow meter in the clinic setting may be an. The a priori ‘increased COPD risk’ group, which comprised 77 of the sample, clearly had worse lung function outcomes. ![]() The availability of reference levels for CPF in the pediatric population, as provided by this study, could be useful for establishing the risk of acute respiratory complications for young patients with weak coughs, particularly those with neuromuscular disease and restrictive pulmonary syndromes. The mean age of the participants was 56 years (range 4098) 45 were men and 45 were ever-smokers (Table 1). CPF values also significantly correlated with other respiratory variables. Fiftieth percentiles were from 147 to 488 liters/min and from 162 to 728 liters/min in females and males, respectively, through an age range of 4-18 yrs, with levels in males being generally higher than those in females at any particular age. Age, even if correlated with CPF, does not add predictive value to the model. Significant relationships were found between CPF and gender, height, and body mass surface (P < 0.001) in both males and females. Other than peak expiratory flow rate, which was normally distributed, all other variables required logarithmic transformation to attain normal distribution. Reference values for CPF were estimated through regression models and calculation of empirical percentiles of data distribution. CPFs were related to anthropometric characteristics, age, and gender by linear multiple regression analysis. Spirometric and peak expiratory flows including CPF data were collected on 649 (341 females, 308 males) healthy children ages 4-18 yrs, using a portable spirometer and a peak flow meter. We describe the distribution of cough peak flows (CPFs) in a random population of healthy children and adolescents.
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